Applications
Our PICO Kits, together with AMULATOR, our data analysis software, allow groundbreaking applications in the areas of:
- Ultra-sensitive protein biomarker detection
- Cellular pathway analysis
- Disruptive cancer research applications
- Innovative assays for pharmaceutical research
- Extracellular vesicle (EV) analysis
Performance
The PICO Products are based on a digital immunoassay concept that utilizes digital PCR (dPCR) technology for readout. This unique approach results in the following powerful features and benefits:
- Absolute quantification of protein targets - no need for external reference
- Multiplex and high-throughput analysis - detect up to 96 samples simultaneously
- Small input sample requirement (down to 0.5 µL) - save on precious samples
- Femtomolar sensitivity - detect the undetectable targets
- Homogeneous, wash-free workflow - no loss of material
Use-cases
The PICO technology expands the advantages of digital PCR into the world of proteins. PICO aims to replace traditional technologies such as western blot, co-immunoprecipitation (coIP), and ELISA, and allows the development of novel quantitative protein assays.
- Superior sensitivity
- Measure absolute amounts of your protein
- More convenient workflow
- Only one instrument required
- Read our application note
- Small input material required
- Higher sensitivity
- No target enrichment required
- Wash-free workflow
- Read our application note
- Detection and quantification of extracellular vesicles (EVs)
- Quantification of post-translational modifications
- Multiplex approaches targeting several targets in parallel
Sample to Result
Actome, in collaboration with your preferred antibody supplier, provides everything required for a comprehensive analysis of your targets. Explore the PICO products offered in our webshop.
- Sample volumes down to 1 µL
- Measurement in the native environment
- Use cells, tissue, or any liquid biological samples
- Quantify proteins, protein interactions and post-translational modifications
- Labeling of antibodies with PICOglue Labels
- Robust & highly efficient PICOglue labeling technology
Products:
- Digital assay with femtomolar sensitivtiy
- Wash-free workflow
- Zero background
Products:
- Compatible with QIAGEN and Stilla dPCR instruments
- Multiplexing: analyze up to 4 different PICOglue Labels simultaneously
- Online analysis software
- Personal cloud-based workspace
- Free registration
- Absolute quantification of targets
- Direct graphical output of data
- Basic statistical evaluation
PICO Products
Say bye to western blot and coIP and hi to our PICO Kits to detect your favourite protein in your lab.
Order in our webshop Contact us for a quote
PICO Services
We offer a comprehensive range of services to help you utilize the PICO technology. These services include the PICO Antibody Quality Control Service to assess your own labeled antibodies, the hassle-free PICO Antibody Labeling Service to conjugate antibodies of your choice with PICOglue Labels, and the development of Custom PICO Assays tailored to your specific needs. Additionally we offer to label your antibodies with Custom DNA Labels.
PICO Antibody Quality Control Service PICO Antibody Labeling Service PICO Custom Assay Development Service Custom DNA Oligo Conjugation ServiceOur partners
Ongoing Public Funded Projects
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Join us in advancing science and technology with PICO, the Absolute Protein Assay. Reach out to us today!
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